Celiac Plexus Neurolysis for Pain Relief in Pancreatic Cancer

Jill C. Moore, MD, and Douglas G. Adler, MD, FACG, FASGE

University of Utah School of Medicine, Department of Internal Medicine, Division of Gastroenterology and Hepatology, Huntsman Cancer Center, Salt Lake City, Utah

Palliation of pain in pancreatic cancer often requires a multidisciplinary approach, with options including oral analgesics, chemoradiotherapy, and celiac plexus neurolysis (CPN). Although CPN may be performed endoscopically, percutaneously, or surgically, endoscopic ultrasonography (EUS)-guided CPN is becoming more commonplace, given the overall improved real-time visualization and reduced risk of major (neurologic) complications. Regardless of the technique used, CPN may have a long-lasting benefit in between 70% and 90% of patients with pancreatic cancer.

J Support Oncol 2009;7:83–87, 90   print e-mail full text 152 kb