Volume 6, Number 5 (May 2008)

Bench to Bedside

199

Outpatient Management of Febrile Neutropenia: Time to Revise the Present Treatment Strategy
Mads Carstensen, MD, and Jens Benn Sørensen, MD

Department of Oncology, Finsen Centre, Rigshospitalet National University Hospital, Copenhagen, Denmark

Outpatient management of adult cancer patients with low-risk febrile neutropenia—namely, patients who are hemodynamically stable, have no organ failure, are able to take oral medications, and do not suffer from acute leukemia—is safe, effective, and comparable to standard hospital-based therapy, based on a pooled analysis of 10 clinical trials.

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PEER VIEWPOINTS
Outpatient Management of Febrile Neutropenia: Concerns for the Future
Heather Cox, PharmD, and Gerald R. Donowitz, MD, Department of Medicine, University of Virginia Health System, Charlottesville

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Outpatient Management of Febrile Neutropenia: Is It Safe Yet?
Tami N. Johnson, PharmD, Yvette A. DeJesus, RN, MSN, Leslie McMahon, RN, MSN, Kenneth V. I. Rolston, MD and Margaret B. Row, MD, MBA, The University of Texas M. D. Anderson Cancer Center, Houston

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221

Quality-of-Life Assessment for Routine Oncology Clinical Practice
Michele Y. Halyard, MD, and Carol Estwing Ferrans, PhD, RN, FAAN

Department of Radiation Oncology, Mayo Clinic, Scottsdale, Arizona, and Department of Medical-Surgical Nursing and the College of Nursing, University of Illinois at Chicago, Chicago, Illinois

Quality-of-life (QOL) data can be a useful predictor of patient response to treatment and survival and can affect decision-making about therapeutic options. This review addresses the questions frequently asked by oncology care providers about the value of QOL assessment and the issues related to it.

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PEER VIEWPOINTS
From Research to Practice: Quality of Life Assessment in Medical Oncology
Betty Ferrell, PhD, FAAN, City of Hope, Duarte, California

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58 kb

Patient-Reported Quality-of-Life Assessment: Sufficient for Clinical Decision-Making?
Sara J. Knight, PhD, University of California at San Francisco, San Francisco, California

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Original Research

234

Does Dietary Counseling Improve Quality of Life in Cancer Patients? A Systematic Review and Meta-analysis
Thorvardur R. Halfdanarson, MD, Eyglo O. Thordardottir, MD, Colin P. West, MD, PhD, and Aminah Jatoi, MD

University of Iowa Hospitals and Clinics, Iowa City, University of Iceland, Reykjavik, and Mayo Clinic College of Medicine, Rochester, Minnesota

Results have been mixed as to whether dietary counseling improves clinical outcomes in cancer patients. A systematic review and meta-analysis of five randomized clinical trials show that dietary counseling does not appear to significantly improve the quality of life of patients with cancer; however, an observed trend toward benefit underscores the need for further study.

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238

What Do Perceived Cognitive Problems Reflect?
Catherine M. Bender, PhD, Maria L. Pacella, BA, Susan M. Sereika, PhD, Adam M. Brufsky, MD, PhD, Victor G. Vogel, MD, MHS, Priya Rastogi, MD, Frances E. Casillo, BSN, Susan M. Richey, BS, and Christopher M. Ryan, PhD

Women with breast cancer frequently report cognitive problems to healthcare providers during and after adjuvant therapy. Our research indicates that, at a minimum, complaints of cognitive problems should prompt additional assessment to clarify the bases of the problem and initiate appropriate intervention.

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How We Do It

243

Management of Hypomagnesemia in Cancer Patients Receiving Chemotherapy
Muhammad Wasif Saif, MD, MBBS

Section of Medical Oncology, Yale University School of Medicine, New Haven, Connecticut

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